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Reported as a Negative scan

Positive for an 8mm Malignancy - Biopsy proven

A) Mammogram

B) BSGI

C) Mammogram

D) BSGI

Images:  AJR Am J Roentgenol. 2014 Feb;202(2):293-8.

Images courtesy of Rhodes, et al. Radiol 2015;vol258

Molecular Imaging

Images Physiology instead of anatomy...

in other words molecular imaging techniques

don't care about how Dense you are!

 

1.  Breast specific gamma imaging

                           (AKA:  BSGI)

Uses 99mTc Sestamibi which is actively taken up by the

mitochondria in your cancer cells, and emits light from

the area of the highest concentration of cancer cells.

Here is a perfect example of how Molecular Imaging 

just does not care about how DENSE you are... it only

cares about your cancer cells.

In the Images over there, you can see how the tumors are 

hidden in the mammogram, but are clearly seen as black 

spots on BSGI, especially in those dense breasts in A and B.

2.  molecular breast imaging

(AKA: MBI)

Also uses 99mTc Sestamibi, but the

difference in Molecular Breast Imaging and

Breast Specific Gamma Imaging (i.e. above)

is that the camera uses a different - NEWER - technology

and is able to find even smaller clusters of cancer cells

taking up the Sestamibi!!!

Molecular Breast Imaging can pick up

even smaller tumors, like this one.........

3.  Positron emission mammography

(AKA:  PEM)

Uses positron technology (!!!WOW!!!)

to detect actively dividing cancer cells, using

18F-FDG, AKA:  RADIOACITVE SUGAR.

This technique is so amazing, it can detect 

tumors as small as 2 (yes TWO), millimeters

Positron Emission Mammography Images reveal Extensive DCIS

Mammogram Negative

Images courtesy of Lorraine Tafra, Anne Arundel Medical Center, Annapolis, MD

In Collaboration With: 

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American College of Nuclear Medicine

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